◀ Back to MTOR

ATG7 — MTOR

Text-mined interactions from Literome

Huang et al., Int J Oncol 2013 : In SK-HEP-1 cells, kaempferol increased the protein levels of p-AMPK, LC3-II, Atg 5, Atg 7 , Atg 12 and beclin 1 as well as inhibited the protein levels of CDK1, cyclin B, p-AKT and p-mTOR
Wang et al., J Ethnopharmacol 2013 (Ischemic Attack, Transient...) : HLJDD also notably elevated the levels of microtubule associated protein1 light chain 3 ( LC3 ), Beclin-1, and other autophagy related genes ( Atgs ) , promoted the activation of extracellular signal regulated kinases ( ERK ), protein kinase B ( Akt ), 3-phosphoinositide dependent kinase ( PDK1 ), and inhibited the activation of mammalian target of rapamycin (mTOR) , c-Jun N-terminal protein kinases (JNK), p38, phosphatase and tensin homolog (PTEN)
Sciarretta et al., Circulation 2012 (Metabolic Syndrome X...) : Restoration of autophagy, through Atg7 reexpression and inhibition of mTORC1 , increased cellular ATP content and reduced endoplasmic reticulum stress, thereby reducing CM death induced by Rheb activation
Crews et al., PloS one 2010 (Alzheimer Disease...) : By immunoblot analysis, compared to controls and AD, in DLB cases levels of mTor were elevated and Atg7 were reduced