Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Peña-Llopis et al., EMBO J 2011 (MAP Kinase Signaling System) : mTORC1 regulates V-ATPase expression both in cells and in mice ... V-ATPase regulation by mTORC1 involves a transcription factor translocated in renal cancer, TFEB
Xu et al., J Biol Chem 2012 : Bafilomycin, an inhibitor of V-ATPase , inhibited EGF stimulated DNA synthesis and mammalian target of rapamycin complex 1 ( mTORC1 ) activation as indicated by a decrease in eukaryotic initiation factor 4E-binding 1 ( 4E-BP1 ) phosphorylation and p70 ribosomal S6 protein kinase (p70S6K) phosphorylation and kinase activity
Zhang et al., Basic Res Cardiol 2012 (Calcium Signaling...) : Inhibition of Na/K-ATPase activates Ca ( 2+ ) /CaMK/mTOR signaling , which promotes myocardial TNF-a protein production and cardiac dysfunction during endotoxemia