Huang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2011
:
It is concluded that the suppression of SARI expression is involved in CML pathogenesis, and BCR-ABL mediates the down-regulation of SARI mRNA expression in K562 cells
Huang et al., Tumour Biol 2011
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Taken together, these data demonstrate that SARI mRNA expression is suppressed by BCR-ABL through the downstream signaling pathways, suggesting SARI as a potential therapeutic target in CML