Gene interactions and pathways from curated databases and text-mining

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AHR — BCRP4

Text-mined interactions from Literome

Ebert et al., Carcinogenesis 2005 (Adenocarcinoma...) : Furthermore, the expression of BCRP is most likely aryl hydrocarbon receptor (AhR) dependent , as treatment of Caco-2 cells with known AhR agonists including 2,3,7,8-tetrachlorodibenzo-p-dioxin, BP, indolo [ 3,2-b ] carbazole and benzo [ k ] fluoranthene increased both mRNA and protein levels of BCRP
Tan et al., Mol Pharmacol 2010 : Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein ( BCRP/ABCG2 ) ... In this study, we show that BCRP induction by AHR ligands occurs in human intestinal, liver, and mammary carcinoma cells and in primary colonocytes and hepatocytes