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AHR — BCRP4
Text-mined interactions from Literome
Ebert et al., Carcinogenesis 2005
(Adenocarcinoma...) :
Furthermore, the expression of
BCRP is most likely
aryl hydrocarbon receptor (AhR) dependent , as treatment of Caco-2 cells with known AhR agonists including 2,3,7,8-tetrachlorodibenzo-p-dioxin, BP, indolo [ 3,2-b ] carbazole and benzo [ k ] fluoranthene increased both mRNA and protein levels of BCRP
Tan et al., Mol Pharmacol 2010
:
Aryl hydrocarbon receptor is a transcriptional
activator of the human breast cancer resistance protein (
BCRP/ABCG2 ) ... In this study, we show that
BCRP induction by
AHR ligands occurs in human intestinal, liver, and mammary carcinoma cells and in primary colonocytes and hepatocytes