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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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BECN1 — CASP10

Text-mined interactions from Literome

Kim et al., Autophagy 2008 (Necrosis...) : Reduction of Beclin 1 levels with beclin 1 siRNA inhibited DISC formation and caspase-3/8 activation in response to CSE
Luo et al., Cell Death Differ 2010 : Apoptosis induced by the proapoptotic protein Bax reduced autophagy by enhancing caspase mediated cleavage of Beclin 1 at D149
Djavaheri-Mergny et al., Oncogene 2010 : Cross talk between apoptosis and autophagy by caspase mediated cleavage of Beclin 1
Seillier et al., Cell Death Differ 2012 : Moreover, silencing the expression of autophagy related genes ( ATG5 or Beclin-1 ) or inhibiting caspase activity significantly decreases cell death induced by TP53INP1