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BMP3 — WNT3

Text-mined interactions from Literome

McGrew et al., Mech Dev 1999 : The co-activation of Wnt signaling and concomitant inhibition of BMP signaling has previously been implicated in vertebrate neural patterning, as evidenced by the combinatorial induction of engrailed-2 and krox-20 in Xenopus
Liu et al., J Biol Chem 2006 : Expression of a mutant Smad1 protein, which can not be phosphorylated in response to BMP, eliminated the inhibitory effect of BMP on Wnt-inducedbeta-catenin accumulation and transcriptional activity
van Bezooijen et al., J Bone Miner Res 2007 : In contrast, sclerostin shared many characteristics with the Wnt antagonist dickkopf-1 in antagonizing BMP stimulated bone formation and BMP- and Wnt induced Wnt reporter construct activation
Patthey et al., PloS one 2008 : By using in vitro assays of neural crest and placodal cell differentiation, we now provide evidence that Wnt signals impose caudal character on neural plate border cells at the late gastrula stage, and that under these conditions, BMP signals induce neural crest instead of rostral placodal cells
Kami et al., PloS one 2008 : Furthermore, BMP2 inhibited Wnt/beta-catenin signaling that promoted CL6 cardiomyogenesis
Patthey et al., Development 2009 : Our results indicate, however, that at this stage BMP signals can induce neural plate border cells only when Wnt activity is blocked, and that the two signals in combination generate epidermal cells
Steventon et al., Development 2009 : By performing tissue recombination experiments and using specific inhibitors of different inductive signals, we show that the first inductive step requires Wnt activation and BMP inhibition , whereas the later maintenance step requires activation of both pathways
Wang et al., Stem cell research 2009 : Interestingly, WNT3a stimulation of hemoangiogenic cell genesis was virtually abolished in the presence of a BMP inhibitor
Miura et al., Dev Biol 2010 : These data indicate that BMP signaling in the epiblast induces Wnt3 and Wnt3a expression to maintain WNT signaling in the VE, resulting in downregulation of Dkk1 to establish the anterior expression domain
Kamiya et al., Curr Mol Pharmacol 2012 (Bone Resorption) : We recently generated an osteoblast targeted deletion of BMP signaling using a Cre-loxP strategy and found that BMP signaling in osteoblasts can inhibit Wnt signaling through the Wnt inhibitors DKK1 and SOST
Choe et al., Neuron 2012 (Agenesis of Corpus Callosum) : Wnt3 expression in the cingulate callosal pathfinding axons is developmentally regulated by another BMP family member, GDF5, which is produced by the adjacent Cajal-Retzius neurons and turns on before outgrowth of the callosal axons
Kim et al., Biochem Biophys Res Commun 2012 (Wnt Signaling Pathway) : During vertebrate heart valve formation, Wnt/ß-catenin signaling induces BMP signals in atrioventricular canal ( AVC ) myocardial cells and underlying AVC endocardial cells then undergo endothelial-mesenchymal transdifferentiation ( EMT ) by receiving this BMP signals
Klaus et al., Proc Natl Acad Sci U S A 2012 (Wnt Signaling Pathway) : Using FACS enrichment of cardiac progenitors in RBPJ and RBPJ/Axin2 mutants, embryo cultures in the presence of the Bmp inhibitor Noggin, and by crossing a Bmp4 mutation into the RBPJ/Axin2 mutant background, we show that Wnt and Bmp4 signaling activate specific and nonoverlapping cardiac-specific genes in the cardiac progenitors : Nkx2-5, Isl1 and Baf60c are controlled by Wnt/ß-catenin , and Gata4, SRF, and Mef2c are controlled by Bmp signaling
Godin et al., Development 1998 : By contrast, BMP7 expression in the metanephric mesenchyme is dependent on proteoglycans and possibly Wnt signaling