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CALM3 — PTH

Text-mined interactions from Literome

Lu et al., J Endocrinol 2011 (Adenoma...) : Blocking of calmodulin and CaMKII activity by the specific antagonists calmidazolium and KN-62 respectively caused a rise in PTH secretion from parathyroid adenoma cells in spite of increased [ Ca ( 2+ ) ] ( i ) ... The inhibitory effect of Ca ( 2+ ) calmodulin on PTH secretion may be due to the absence of synaptotagmin 1 protein in parathyroid adenomas, as demonstrated by western blot analysis ... Taken together, these results show that calmodulin negatively contributes to the regulation of PTH secretion in parathyroid adenoma, at least partially via a CaMKII pathway