Gene interactions and pathways from curated databases and text-mining

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CAPN9 — CTNNB1

Text-mined interactions from Literome

Li et al., Proc Natl Acad Sci U S A 2002 : Ca ( 2+ ) release from internal stores results in nuclear export and calpain mediated degradation of beta-catenin in the cytoplasm ... We conclude that Gq signaling promotes nuclear export and calpain mediated degradation of beta-catenin , which therefore contributes to the inhibition of Wnt/beta-catenin pathway
Abe et al., Neuron 2007 (Translocation, Genetic) : Here, we show that, in hippocampal neurons, NMDA-receptor dependent activation of calpain induced the cleavage of beta-catenin at the N terminus, generating stable, truncated forms
Lee et al., J Neurochem 2008 : Pharmacological studies and in vitro calpain-1 proteolysis confirmed that in the glutamate treated hippocampus, calpain-1 mediated decrease of beta-catenin could occur independently of GSK-3beta and of proteasome, and that GSK-3beta degradation is independent of calpain-1