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CASP4 — ETS1
Text-mined interactions from Literome
Pei et al., Cancer Res 2005
(Colonic Neoplasms) :
To determine whether
ETS1 activates the transcription of
caspase-1 , luciferase reporters driven by the wild-type and mutant caspase-1 promoters were generated ... Wild-type
caspase-1 promoter ( pGL3-ICE ) was strongly
transactivated by
ETS1 and this transactivation was dramatically diminished by the mutation of the potential Ets binding site ( -525 bp ) ... Taken together,
ETS1 transcriptionally
induces the expression of
caspase-1 ; as such, the regulatory control of caspase-1 expression by ETS1 may underlie the apoptotic susceptibility modulated by ETS1 in specific tumor cells ... Taken together,
ETS1 transcriptionally
induces the expression of
caspase-1 ; as such, the regulatory control of caspase-1 expression by ETS1 may underlie the apoptotic susceptibility modulated by ETS1 in specific tumor cells
Lehnardt et al., J Immunol 2007
:
Instead, interaction of GBS with TLR2 results in formation and
activation of
caspase-8 , a process that involves the transcription factor family
Ets