◀ Back to TLR7

CASP9 — TLR7

Text-mined interactions from Literome

Mariathasan et al., Nature 2004 (Inflammation...) : Unexpectedly, Ipaf-deficient macrophages activated caspase-1 in response to TLR plus ATP stimulation but not S. typhimurium
Miggin et al., Proc Natl Acad Sci U S A 2007 : However, we found that Mal was cleaved by caspase-1 and that inhibition of caspase-1 activity blocked TLR2- and TLR4 mediated NF-kappaB and p38 MAP kinase activation but not IL-1 or TLR7 signaling, which are Mal independent
Hewinson et al., J Immunol 2008 (Ion Channel Gating) : P2X(7) receptors ( P2X(7)Rs ) are ATP gated ion channels that trigger caspase-1 activation in the presence of TLR ligands
Netea et al., Blood 2009 (Inflammation) : Controversy has arisen whether Toll-like receptor ( TLR ) ligands alone can activate caspase-1 for release of interleukin-1beta (IL-1beta)
Hurst et al., Immunobiology 2009 (Antiphospholipid Syndrome) : Determination of expression-levels using real-time RT-PCR showed significantly augmented TLR dependent IL-1beta and caspase-1 expression
Nicholas et al., Cell Mol Life Sci 2011 : Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8 mediated activation of caspase 1 and interleukin-1ß ... Specific inhibition of the XOD activity attenuates TLR7/8 mediated activation of caspase 1 and IL-1ß release