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CCNB1 — MAPK3
Text-mined interactions from Literome
Huo et al., Biol Reprod 2004
(MAP Kinase Signaling System) :
Both U0126 and roscovitine inhibited the phosphorylation of
MAPK and p90rsk, and the synthesis of
cyclin B1 stimulated by proteasome inhibitors
Smythe et al., Mol Reprod Dev 2005
:
Inhibition of
MAPK signaling by U0126 was capable of delaying but not permanently
blocking Cdc2/cyclin B activation and GVBD in 5-HT treated oocytes and subsets of NSW treated oocytes
Dumesic et al., J Cell Biol 2009
(Neoplasms) :
Unlike fibroblasts, in which Erk1/2 loss decreases cyclin D1 expression and induces G1/S arrest,
Erk1/2 loss in epithelial cells
reduces cyclin B1 and c-Fos expression and induces G2/M arrest while disrupting a gene regulatory network centered on cyclin B1-Cdc2