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CD3E — JAG1
Text-mined interactions from Literome
Recio et al., J Immunol 2007
(Lymphopenia...) :
All tested patients shared similar immunological features such as a partial
TCR/CD3 expression defect, mild alphabeta and gammadelta T lymphocytopenia, poor in vitro proliferative
responses to
Ags and mitogens at diagnosis, and very low TCR rearrangement excision circles and CD45RA ( + ) alphabeta T cells
Theodore et al., J Immunol 1996
:
CD4 participation in TCR/CD3 associated activation through interaction with the MHC class II
Ags results in formation of a
CD4-TCR/CD3 complex capable of maximal signal transduction