Gene interactions and pathways from curated databases and text-mining

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CD80 — IL5

Text-mined interactions from Literome

Rafiq et al., Clin Exp Immunol 2000 : In accordance with this, CD80 and phorbol myristate acetate ( PMA ) ( without anti-CD3 or calcium ionophore ) were sufficient to induce production of IL-5 and IL-13, but not of IL-4
Blanchet et al., Am J Respir Crit Care Med 2004 (Alveolitis, Extrinsic Allergic) : To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor, interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula stimulated cells