Gene interactions and pathways from curated databases and text-mining

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CEACAM5 — PARP11

Text-mined interactions from Literome

Liu et al., Clin Cancer Res 2007 (Brain Neoplasms...) : The pan-caspase inhibitor Z-VAD-FMK and the caspase-8 inhibitor Z-IETD-FMK, but not the caspase-9 inhibitor Z-IEHD-FMK, protected glioma cells from MV-CEA/RT induced cleavage of poly ( ADP-ribose ) polymerase ( PARP ), indicating that the apoptotic death in combination treated cells is mostly mediated via the extrinsic caspase pathway
Liu et al., Gene Ther 2008 (Neoplasms) : The pan-caspase inhibitor Z-VAD-FMK and caspase-8 inhibitor Z-IETD-FMK, but not the caspase-9 inhibitor Z-IEHD-FMK, protected tumor cells from MV-CEA/GA induced PARP activation, indicating that apoptosis in combination treated cells occurs mainly via the extrinsic caspase pathway