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CHRD — FGF17

Text-mined interactions from Literome

Londin et al., Dev Biol 2005 : We observed that FGF signaling is required for chordin expression but that it also acts via other mechanisms to repress BMP transcription during late blastula stages
Maegawa et al., Development 2006 : By contrast, when FGF signaling is inhibited, beta-catenin did not induce goosecoid and chordin , repress bmp4 expression or induce a dorsal axis ... These experiments show that FGF dependent organizer function operates through both bozozok RNA accumulation and a pathway consisting of beta-catenin -- > Squint -- > FGF -- > Chordin, in which each component is sufficient for expression of the downstream factors of the pathway, and in which Nodal signaling is required for FGF gene expression and FGF signaling is required for Squint induction of chordin
Varga et al., Mech Dev 2007 : Chordin expression, mediated by Nodal and FGF signaling, is restricted by redundant function of two beta-catenins in the zebrafish embryo