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CDK8 — CNTF

Text-mined interactions from Literome

Steinberg et al., Endocrinology 2006 (Obesity) : Intracerebroventricular CNTF ( Ax15 ) reduced food intake, increased arcuate nucleus (ARC) signal transducer and activator of transcription 3 phosphorylation, and reduced AMPK signaling but not in the paraventricular nucleus ( PVN ), posterior hypothalamus, or cortex ... Both leptin and CNTF reduced AMPK activity and acetyl-coenzyme A carboxylase phosphorylation in the ARC and PVN of control fed mice
Ambati et al., Biofactors 2007 (Body Weight) : Leptin and CNTF increased ARC-ME mRNA levels of signal transducer and activator of transcription 3 ( STAT3 ) by 64.5 and 124.7 % ( p < 0.01 ), suppressor of cytokine signaling 3 ( SOCS3 ) by 258.9 and 1063.9 % ( p < 0.01 ), cocaine and amphetamine regulated transcript ( CART ) by 102.7 and 123.1 % ( p < 0.01 ), and proopiomelanocortin ( POMC2 ) by 374.1 and 264.9 % ( p < 0.01 ), respectively