Gene interactions and pathways from curated databases and text-mining

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COL1A2 — TGFB2

Text-mined interactions from Literome

Wendling et al., Mol Pharmacol 2003 : 5-fluorouracil blocks transforming growth factor-beta induced alpha 2 type I collagen gene ( COL1A2 ) expression in human fibroblasts via c-Jun NH2-terminal kinase/activator protein-1 activation
Kimoto et al., Invest Ophthalmol Vis Sci 2004 (MAP Kinase Signaling System) : mRNA expression of COL1A1 and COL1A2 and type I collagen synthesis were activated by TGF-beta 2
Nieto et al., J Biol Chem 2005 (Fibrosis) : S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter
Itoh et al., Exp Eye Res 2007 : To examine the effects of simvastatin or Y27632 on COL1A2 promoter activity induced by TGF-beta2 , luciferase reporter assays were also performed ... Preincubation of ARPE-19 with simvastatin ( 5 microM ) or Y27632 ( 10 microM ) significantly prevented TGF-beta2 induced COL1A1 and COL1A2 gene expression ... Constitutively active RhoA increased COL1A2 promoter activity in the presence or absence of TGF-beta2