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CCK — CPA1

Text-mined interactions from Literome

Murthy et al., J Biol Chem 2000 : CCK-8 and SP increased only Galpha ( q/11 ), and CPA increased only Galpha ( i3 ) in caveolin immunoprecipitates ; caveolin and other G proteins were not increased
Cao et al., Molecular brain 2012 (Visceral Pain) : In contrast, CCK had no effect on CPA induced by non-nociceptive aversive stimulus ( U69,593 )
Yu et al., PloS one 2012 (Morphine Dependence...) : To investigate the effects of endogenous and exogenous CCK on negative components of morphine withdrawal, we evaluated the effects of CCK receptor antagonists and CCK-8 on the naloxone precipitated withdrawal induced conditioned place aversion (CPA) ... Similarly, CCK-8 ( 0.1-1 µg, i.c.v. ) significantly attenuated naloxone precipitated withdrawal induced CPA , and this inhibitory function was blocked by co-injection with L-364,718 ... Microinjection of L-364,718, LY-288,513 or CCK-8 to saline pretreated rats produced neither a conditioned preference nor aversion, and the induction of CPA by CCK-8 itself after morphine pretreatments was not significant ... Our study identifies a different role of CCK1 and CCK2 receptors in negative affective components of morphine abstinence and an inhibitory effect of exogenous CCK-8 on naloxone precipitated withdrawal induced CPA via CCK1 receptor