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CSF2 — CUL1
Text-mined interactions from Literome
Pyatt et al., Mol Pharmacol 1996
:
Support for this conclusion came from experiments demonstrating that 1 ) mutant mice strains constitutively lacking a SCF-responsive population of HPC [ White spotted ( W/WV ) and Steel ( SI/SId ) ] are unresponsive to xanthine/XO- and
SCF induced enhancement of
GM-CSF and 2 ) 3,4-epoxybutene, which selectively abrogates SCF synergy with GM-CSF, inhibits xanthine/XO induced enhancement
Cardier et al., Stem Cells 1997
:
Moreover,
GM-CSF in the
presence of
SCF and IL-3 potentiates the HPP-CFC formation ( i.e., an increase of 3.1-fold compared to the effect induced by SCF+IL-3 ) with strong inhibitory effects on the number and size of megakaryocyte colonies