Kim et al., Mol Cell Biol 2004
:
Jab1/CSN5 , a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation ... The inhibition of endogenous Jab1/CSN5 expression by small interfering RNA ( siRNA ) induces Smad7 expression
Chaverneff et al., J Neurochem 2009
(Hypoglycemia) :
Inhibitors of casein kinase II ( CK2 ) activity reduced the ( BMP7 + BDNF ) -induced Smad phosphorylation, and this trophic factor combination increased CK2 activity in hypoglycemic cultures