Kim et al., Am J Physiol Endocrinol Metab 2008
:
The FSP27 transcript is inversely regulated by TNF-alpha and insulin , consistent with an antilipolytic function
Wurm et al., Cytokine 2008
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Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway ... Inhibition of the phosphatidylinositol 3-kinase by wortmannin or the mammalian target of rapamycin by rapamycin did not influence insulin mediated CXCL8 induction ... In contrast, blockage of the ERK-specific MAP kinase MEK with PD98059, that prevents phosphorylation of ERK1/ERK2, abrogated insulin induced CXCL8 release in primary monocytes