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CXCR3 — IL5
Text-mined interactions from Literome
Moed et al., Clin Exp Allergy 2004
(Dermatitis, Allergic Contact) :
A second group of AID, which included VD ( 3 ), HC and DMF, suppressed mainly type-1 T cell responses, as revealed by strong interference with IFN-gamma production and
CXCR3 expression, and limited
effects on either or both
IL-5 and CCR4 expression
Schmitz et al., Brain Behav Immun 2013
:
Oppositely,
CXCR3-deficiency had no protective effect after traumatic nerve injury but reduced EAE evoked hyperalgesia and was associated with reduced clinical EAE scores, a reduction of the pro-inflammatory cell infiltration and
reduced upregulation of interferon gamma and
interleukin-17 in the spinal cord