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DES — MAPK8

Text-mined interactions from Literome

Zell et al., Life Sci 2002 (Breast Neoplasms) : In an attempt to determine the upstream signaling pathway, the effects of PDB or DES on the mitogen activated protein kinase ( MAPK ) levels were determined by western blot analysis in the presence and absence of PD098059, a specific inhibitor of mitogen activated protein kinase kinase ( MAPKK ) ... The phospho-MAPK ( p44/42 ) levels, an activated form of MAPK, increased in DES and PDB stimulated cells whereas PD098059 treatment inhibited this increase
Blunt et al., Am J Physiol Heart Circ Physiol 2007 (Reperfusion Injury) : These findings are consistent with the hypothesis that H ( 2 ) O ( 2 ) -induced activation of p38 MAPK and subsequent HSP25/27 translocation attenuates desmin degradation brought about by calpain-1 activation in ischemia reperfused hearts