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Liu et al., Acta Pharmacol Sin 2002 : Effects of PBC on expression of intercellular adhesion molecule-1 ( ICAM-1 ), vascular cell adhesion molecule-1 ( VCAM-1 ), P-selectin , a nd E-selectin in human umbilical vein endothelial cells were examined
Li et al., Endothelium : journal of endothelial cell research 1998 : To elucidate the mechanisms of the inhibition on adhesion, PBC effects on the Ox-LDL induced expression of P-selectin , on the synthesis of von Willebrand factor (vWF) and prostacyclin ( PGI2 ) were examined ... PBC 25, 50 and 75 micromol/L inhibited the Ox-LDL induced adhesion index from 37.3 % to 19.7, 16.6 and 14.6 % respectively ( p all < 0.05 ), and inhibited the Ox-LDL induced expression of P-selectin from 293.0 ng/ml to 180.0, 132.9 and 132.6 ng/ml respectively