Gene interactions and pathways from curated databases and text-mining

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EDN1 — ROCK1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: ROCK1 → EDN1 (increases, EDN1 Activity)
    Evidence: p160ROCK is a mediator of endothelin-1 (ET-1) induction of the brain natriuretic peptide promoter by RhoA in hypertrophying cardiac myocytes (40)