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EGR1 — OPN1LW
Text-mined interactions from Literome
Miller et al., Mol Cell Biol 2012
:
While GNRH mediated phosphorylation of
CBP at Ser436
increased the interaction with
Egr-1 on the Lhb promoter, loss of this phosphorylation site eliminated GNRH mediated Lhb expression in LßT2 cells ... Our results show that GNRH mediated phosphorylation of
CBP at Ser436 is
required for
Egr-1 to activate Lhb expression and is a requirement for normal fertility in female mice
Webster et al., J Biol Chem 2013
:
TNF, acting via NF-?B, did not change the levels of CREB, Sp1, or
Egr-1 binding to the Ga ( s ) promoter, but it
induced a significant reduction in the level of
CBP