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ETS2 — MMP3

Text-mined interactions from Literome

Westermarck et al., FASEB J 1999 (Neoplasm Invasiveness...) : This review will summarize the current view on the role of MMPs in tumor growth, invasion, and survival, and focus on the role of mitogen activated protein kinases and AP-1 and ETS transcription factors in the regulation of MMP gene expression during invasion process
Kondo et al., Int J Cancer 2005 (Carcinoma, Squamous Cell...) : LMP1 transfected cells with 2G/2G genotype expressed MMP1, which was abolished by activator protein-1 (AP1) dominant negative ( DN ) and Ets-DN. LMP1 also induced active MMP3 , which can cleave latent MMP1, and AP1-DN and Ets-DN suppressed the MMP3 expression