Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Jensen-Urstad et al., J Lipid Res 2013 : Rapamycin induced inhibition of mammalian/mechanistic target of rapamycin complex 1 ( mTORC1 ), a mediator of the feeding/insulin signal to induce lipogenesis, reduced FAS phosphorylation, increased cytoplasmic FAS enzyme activity, and increased PPARa target gene expression
Chiang et al., FEBS Lett 2007 (Breast Neoplasms) : The use of pharmacological inhibitors revealed that the modulation of Akt, mTOR and JNK phosphorylation was required for diosgenin induced FAS suppression
Yue et al., BMB Rep 2010 : The expressions of CCAAT/enhancer binding protein-alpha ( C/EBP-alpha ) and fatty acid synthase (FAS) protein were gradually enhanced during the 10-day duration while mTOR phosphorylation and sterol-regulatory-element binding protein ( SREBP)-1c protein were induced on day 4