Gene interactions and pathways from curated databases and text-mining

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FCGR2B — IL4

Text-mined interactions from Literome

Pricop et al., J Immunol 2001 : Fc gamma RIIb2 expression is increased by IL-4 and decreased by IFN-gamma, in contrast to the activating receptor, Fc gamma RIIa, which is increased by IFN-gamma and decreased by IL-4
Tridandapani et al., J Biol Chem 2002 : We also report that the expression of FcgammaRIIb is highly up-regulated by interleukin-4 , a Th2 cytokine, and that the up-regulation of FcgammaRIIb results in a decrease in the phagocytic efficiency of interleukin-4 treated THP-1 cells
Joshi et al., Mol Immunol 2006 : Here, we extend these findings to demonstrate that the IL-4 induced upregulation of FcgammaRIIb is synergistically enhanced by the addition of IL-10, both at the protein and the mRNA level
Pilling et al., PloS one 2009 : In addition, IL-4 , IL-12, IL-13, IFN-gamma, and SAP differentially regulate the expression of CD32 , CD163, CD172a, and CD206 on both macrophages and fibrocytes