Gene interactions and pathways from curated databases and text-mining

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FGB — NFKB1

Text-mined interactions from Literome

Guo et al., Thromb Haemost 2004 (Inflammation) : From our findings, we conclude that fibrinogen regulates NF-kappaB activation and expression of inflammatory chemokines in endothelial cells and may be involved in mediating inflammatory processes
Malaver et al., Journal of thrombosis and haemostasis : JTH 2009 : Two specific unrelated inhibitors of NF-kappaB activation, BAY 11-7082 and Ro 106-9920, reduced PAC-1 and fibrinogen binding to integrin alpha ( IIb ) beta3 and restricted platelet spreading on immobilized fibrinogen
Sitrin et al., J Immunol 1998 (Leukemia, Monocytic, Acute) : Mononuclear phagocytes are exposed to fibrinous provisional matrix throughout migration into inflammatory foci, so this study was undertaken to determine whether fibrinogen triggers activation of NF-kappa B transcription factors ... NF-kappa B activation, minimal in unstimulated cells, was substantially up-regulated by fibrinogen ... Blocking mAbs against CD18 and CD11b abrogated fibrinogen induced NF-kappa B activation