◀ Back to APOB
APOB — FGF2
Text-mined interactions from Literome
Chen et al., Circulation 2000
:
Cytotoxic
effects of
ox-LDL on ECs are attributable in part to suppression of
bFGF expression
Cucina et al., Atherosclerosis 2006
(Atherosclerosis) :
The purpose of our study was to investigate the
effects of mildly oxidized
LDL ( minimally modified LDL : MM-LDL ) and HDL, administrated alone or in combination, on the production and release of
basic fibroblast growth factor (bFGF) by bovine aortic smooth muscle cells ( SMCs ) in culture ... MM-LDL and HDL have opposite effects on aortic SMCs :
MM-LDL increases both
bFGF production and release and SMC proliferation, while HDL decreases both bFGF production and release and SMC proliferation
Davies et al., Biochim Biophys Acta 1982
:
Platelet derived growth factor ( PDGF ) and
fibroblast growth factor ( FGF ) significantly
stimulated the binding of
LDL to high affinity receptors of smooth muscle cells and fibroblasts ...
LDL binding was stimulated in the
presence of PDGF or
FGF but not after their removal within 8 h of entry into the cell cycle
Hsu et al., J Biol Chem 1994
:
In studies reported herein, we show
bFGF increases
low density lipoprotein (LDL) binding, uptake, and degradation in arterial smooth muscle cells in a dose dependent manner
Chen et al., Proc Assoc Am Physicians 1997
(Arteriosclerosis...) :
In endothelial cells in culture,
ox-LDL suppressed
bFGF expression and DNA synthesis in a dose dependent manner