Gene interactions and pathways from curated databases and text-mining

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FGF22 — NCAM2

Text-mined interactions from Literome

Francavilla et al., J Cell Sci 2007 : Furthermore, our data show that NCAM inhibits the binding of FGF to its high-affinity receptor in a competitive manner, providing the mechanisms for the NCAM mediated suppression of FGF function
Kiselyov et al., Neurosci Lett 2009 : C3, a synthetic peptide binding to the Ig1 module of the neural cell adhesion molecule ( NCAM ) has previously been identified and shown to inhibit NCAM homophilic binding and NCAM mediated activation of the fibroblast growth factor ( FGF ) receptor ( FGFR )
Chen et al., J Neurosci Res 2010 : Activation of fibroblast growth factor ( FGF ) receptors ( FGFRs ) both by FGFs and by the neural cell adhesion molecule ( NCAM ) is crucial in the development and function of the nervous system
Ono et al., J Biol Chem 2012 : Taken together, these results suggest that polySia-NCAM might be involved in the regulation of FGF2-FGF receptor signaling through the direct binding of FGF2 in a manner distinct from heparan sulfate