Gene interactions and pathways from curated databases and text-mining

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FGF3 — SPP1

Text-mined interactions from Literome

Leali et al., J Immunol 2003 : In vivo, FGF2 caused OPN expression in newly formed endothelium of the chick embryo chorioallantoic membrane (CAM) and of murine s.c. Matrigel plug implants
Li et al., J Appl Physiol 2004 (Anoxia) : In contrast, FGF-1 induced OPN expression was blocked by inhibitors of JNK or MEK1/2 but not of PI3K, p70S6K, or p38MAPK
Ben-Zvi et al., J Cell Sci 2006 : Expression of osteopontin (OPN) , which is directly upregulated by FGF in chondrocytes, was stimulated by lower levels of FGF in cells expressing SOCS1 compared with parental cells
Nakayama et al., J Oral Sci 2012 : In human osteoblast-like Saos2 cells, FGF2 increased the expression of the osteopontin ( SPP1, 16.7-fold ), interleukin-8 ( IL8, 6.4-fold ) and IL11 ( 4.8-fold ) genes
Rodan et al., J Biol Chem 1989 : Opposing effects of fibroblast growth factor and pertussis toxin on alkaline phosphatase, osteopontin , osteocalcin, and type I collagen mRNA levels in ROS 17/2.8 cells