Gene interactions and pathways from curated databases and text-mining

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FOXO3 — STAT3

Text-mined interactions from Literome

Yang et al., J Biol Chem 2009 : Furthermore, FoxO1 binds to STAT3 and prevents STAT3 from interacting with the SP1.POMC promoter complex, and consequently, inhibits STAT3 mediated leptin action
Oh et al., J Biol Chem 2011 : We further show that STAT3 binds directly to FoxO1 or FoxO3a promoter and that STAT3-deficiency resulted in down-regulation of the expression of FoxO1, FoxO3a and FoxO-target genes ( I?B and p27Kip1 ) ... We further show that STAT3 binds directly to FoxO1 or FoxO3a promoter and that STAT3-deficiency resulted in down-regulation of the expression of FoxO1, FoxO3a and FoxO-target genes ( I?B and p27Kip1 )