Gene interactions and pathways from curated databases and text-mining

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CDK5 — GCHFR

Text-mined interactions from Literome

Takahashi et al., J Neurochem 2004 (Amyotrophic Lateral Sclerosis...) : Our results provide direct evidence that the pathogenesis of motor neuron disease in the mutant SOD1 mice is independent of the Cdk5 activation by p35 or p25
Gompel et al., Neurosignals 2004 (Teratocarcinoma) : In contrast, the activity of CDK5/p35 dramatically increases, probably as a result of an enhanced expression of p35 in a stable CDK5 level background
Schmid et al., Mol Neurobiol 2006 (Brain Ischemia...) : p35 and its isoform p39 bind to, and thereby activate , Cdk5