Gene interactions and pathways from curated databases and text-mining

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FOS — GHSR

Text-mined interactions from Literome

Hewson et al., Diabetes 2002 : Furthermore, the GHRP-6 induced Fos response was twofold greater in obese leptin- and insulin-resistant Zucker rats compared with lean controls
Yi et al., Eur J Neurosci 2008 : In the present study we show that i.v. administration of GHRP-6 decreases light induced Fos expression at ZT13 in the rat SCN by 50 %, indicating that light induced changes in the SCN Fos expression can also be reduced by GHRP-6 ... However, light induced Fos expression in the mice SCN was not blocked by GHRP-6
Kaur et al., Alcohol Clin Exp Res 2010 (Disease Models, Animal) : In Experiment 3, D-Lys3-GHRP-6 reduced the induction of c-Fos by intraperitoneal ethanol in the pIIIu but had no effect in the VTA
Pirnik et al., Neurochem Int 2011 : In the present study, we compared the effect of subcutaneously administered ghrelin and its three stable agonists : Dpr ( 3 ) ghr ( [ Dpr ( N-octanoyl ) ( 3 ) ] ghrelin ) ( Dpr - diaminopropionic acid ), YA GHRP-6 ( H-Tyr-Ala-His-DTrp-Ala-Trp-DPhe-Lys-NH ( 2 ) ), and JMV1843 ( H-Aib-DTrp-D-gTrp-CHO ) on the Fos expression in food intake-responsive brain areas such as the hypothalamic paraventricular ( PVN ) and arcuate (ARC) nuclei, the nucleus of the solitary tract (NTS), and area postrema ( AP ) in male C57BL/6 mice
Dickson et al., J Endocrinol 1995 (Growth Disorders) : First, we demonstrated that peripherally administered GHRP-6 induces Fos expression in the arcuate nucleus of GH-deficient animals ( dw/dw rats and lit/lit mice )
Dickson et al., Neuroendocrinology 1997 : Intracerebroventricular sandostatin injection attenuated the GHRP-6 induced Fos response, from 53 +/- 6 nuclei/section in the i.c.v. aCSF/i.v. GHRP-6 group, to 39 +/- 5 nuclei/section in the i.c.v. sandostatin/i.v. GHRP-6 group