UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to JAK2

GNAI1 — JAK2

Pathways - manually collected, often from reviews:

NCI Pathway Database CXCR4-mediated signaling events: SDF1/CXCR4/JAK2 complex (CXCL12-CXCR4-JAK2) → Gi family/GTP/RGS1 complex (GNAI2_GNAI3_GNAO1_GNAO1_GNAZ_GNAI1-RGS1) (modification, activates)
Wang et al., Blood 2000, Zhang et al., Blood 2001, Okabe et al., J Hematother Stem Cell Res 2002, Le et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction