Gene interactions and pathways from curated databases and text-mining

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GNRH1 — GPR68

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Prentice et al., BMC medicine 2007 (Disease...) : Kisspeptins and their G-protein coupled receptor , GPR54 are required for GnRH release and have been associated with anti-metastatic tumour cell behaviour in model systems
Richard et al., J Neuroendocrinol 2008 : Conversely, GPR54 is up-regulated by GnRH , which exclusively targets gonadotrophs
Larco et al., Endocrinology 2013 : Because the cognate GnRH receptor is a G protein coupled receptor, we examined whether GnRH- ( 1-5 ) regulates migration by also activating a G protein coupled receptor ... Using a high-throughput ß-arrestin recruitment assay, we identified an orphan G protein coupled receptor ( GPR173 ) that was specifically activated by GnRH- ( 1-5 )