◀ Back to GNRH1
GNRH1 — GPR68
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
GNRH1
→
GPR68
(reaction)
Rubio et al., Genomics 1999, Dowal et al., J Biol Chem 2006, Lambert et al., Science signaling 2008, Amatruda et al., Proc Natl Acad Sci U S A 1991, Ferguson et al., J Biol Chem 1986, Chen et al., Biochim Biophys Acta 1996
Text-mined interactions from Literome
Prentice et al., BMC medicine 2007
(Disease...) :
Kisspeptins and their
G-protein coupled receptor , GPR54 are
required for
GnRH release and have been associated with anti-metastatic tumour cell behaviour in model systems
Richard et al., J Neuroendocrinol 2008
:
Conversely,
GPR54 is
up-regulated by
GnRH , which exclusively targets gonadotrophs
Larco et al., Endocrinology 2013
:
Because the cognate GnRH receptor is a G protein coupled receptor, we examined whether
GnRH- ( 1-5 )
regulates migration by also activating a
G protein coupled receptor ... Using a high-throughput ß-arrestin recruitment assay, we identified an orphan
G protein coupled receptor ( GPR173 ) that was specifically
activated by
GnRH- ( 1-5 )