Gene interactions and pathways from curated databases and text-mining

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GPX1 — IRF6

Text-mined interactions from Literome

Catalá et al., Mol Cell Biochem 2002 : Although no significant effects were observed on glutathione reductase activity, both LPS and cytokines induced an important inhibition of glutathione peroxidase which can justify the lipid peroxidation previously observed both in liver during reversible endotoxic shock and in cultured hepatocytes after treatment with endotoxin
Zeng et al., Arch Biochem Biophys 2008 (Carcinoma, Hepatocellular...) : LPS induced the decreases of cytoplasmic glutathione peroxidase ( GPx-1 ) mRNA expression and activity, and the increases of reactive oxygen species ( ROS ) level, intracellular and extracellular nitric oxide ( NO ) levels, inducible nitric oxide synthase (iNOS) mRNA expression and activity, and serum amyloid A1 (SAA1) mRNA expression and secreted protein level in hepatoma HepG2 cells
Iszard et al., Toxicology 1995 : Cd significantly increased, whereas LPS reduced , the activities of selenium dependent glutathione peroxidase and glutathione reductase