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GTF2I — HSPA5

Text-mined interactions from Literome

Hong et al., J Biol Chem 2005 : Lastly, using stable cell lines with suppressed TFII-I levels, we show that TFII-I is required for optimal induction of Grp78 by ER stress ... Our studies provide a molecular link that connects the c-Src tyrosine kinase transduction pathway to ER stress induced transcriptional activation of Grp78 mediated by TFII-I
Misra et al., J Cell Biochem 2011 (Prostatic Neoplasms) : Ligation of GRP78 with a2 M also upregulates TFII-I , which binds to the GRP78 promoter and enhances GRP78 synthesis ... In conclusion, we demonstrate that not only does cell surface GRP78 regulate apoptosis, but it also regulates Ca ( 2+ ) homeostasis by controlling cell surface localization of TFII-I