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EGR1 — HSD11B2

Text-mined interactions from Literome

Heiniger et al., FASEB J 2003 (Anoxia...) : Overexpression of Egr-1 reduced endogenous 11beta-HSD2 activity in LLC-PK1 cells, indicating that MAPK ERK is involved in the regulation of 11beta-HSD2 in vitro
Tsugita et al., Life Sci 2008 : In contrast, the transcriptional activity of 11beta-HSD-2 was decreased during the same stimuli, and another inflammation induced transcription factor Egr-1 might have mediated the effect by interfering with the effect of Sp1, which maintains the basal expression of 11beta-HSD-2