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ADCY5 — HTR1B

Text-mined interactions from Literome

Akin et al., Br J Pharmacol 2002 : 4. Naratriptan induced stimulation of 5-HT(1B) receptors resulted only in adenylate cyclase inhibition, whereas stimulation of these receptors by sumatriptan or eletriptan produced vasocontraction as well ... Hence, we concluded that the 5HT(1B) mediated inhibition of adenylate cyclase was not a sufficient condition to couple the receptor stimulation to vasocontraction
Januel et al., Psychiatry Res 2002 : Using the same technique in the present study, we found that lithium significantly reduced the inhibition of adenylate cyclase activity induced by 5-HT(1B) receptor activation ... Moreover, a correlation between the percentage of 5-HT(1B) receptor dependent adenylate cyclase inhibition and the clinical benefit of lithium was established, suggesting 5-HT(1B) receptors may be a target for the therapeutic effect of lithium
Schoeffter et al., Naunyn Schmiedebergs Arch Pharmacol 1989 : 5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity