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CA2 — HTR2A

Text-mined interactions from Literome

Tomiyoshi et al., Biol Psychiatry 1999 : Our present data suggest that the enhancement of 5-HT2A induced Ca2+ responses persisted after remission in depressed patients, and that the duration of the remission is a factor varying the intracellular basal Ca2+ levels
Nilsson et al., Life Sci 1991 : Pharmacological studies indicated that the Ca2+ responses were mediated by 5HT2 receptors
Kusumi et al., Life Sci 1991 : This 5-HT2 mediated Ca2+ response was not significantly affected by the time of blood sampling, gender, meal or exercise
Dai et al., Psychopharmacologia 2011 : Phospholipase C, Ca2+ , and calmodulin signaling are required for 5-HT2A receptor mediated transamidation of Rac1 by transglutaminase
Dickenson et al., Biochem Pharmacol 1994 : These data suggest that in cultured guinea-pig aortic smooth muscle cells bradykinin B2- and 5-HT2-receptor activation stimulates the release of Ca2+ from intracellular stores and Ca2+ influx through Ca2+ entry pathways in the plasma membrane
Ozaki et al., Biol Psychiatry 1996 : Lack of association of Val447 and Tyr452 to SAD is consistent with observations showing normal 5-HT2A receptor Ca2+ response in platelets with this disorder, however, the two 5-HT2A amino acid substitutions may lead to differences in behavioral phenotypes
Ozaki et al., J Neurochem 1997 : Platelet 5-HT2A binding and 5-HT induced Ca2+ response were compared in eight 452His/452His homozygous and eight 452His/452Tyr heterozygous individuals matched for sex, age, and diagnosis ( all were patients with seasonal affective disorder )
Farré et al., Methods Find Exp Clin Pharmacol 1997 : Dotarizine is a new diphenylmethylpiperazine derivative with Ca2+ channel blocking properties and inhibitory effects on 5-HT2A and 5-HT2C receptors