Gene interactions and pathways from curated databases and text-mining

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CASP4 — IFIH1

Text-mined interactions from Literome

Barral et al., J Virol 2007 : Instead, degradation of MDA-5 in poliovirus infected cells occurs in a proteasome- and caspase dependent manner
Kuo et al., PloS one 2013 (Enterovirus Infections) : Furthermore, we also show that EV71 infection enhances MDA5 degradation and that the degradation could be inhibited by a broad spectrum caspase inhibitor