Gene interactions and pathways from curated databases and text-mining

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IGF1 — MMP3

Text-mined interactions from Literome

Hui et al., Ann Rheum Dis 2001 : IGF1 can also down regulate IL1alpha or IL1alpha + OSM induced MMP-1, MMP-3 , MMP-8, and MMP-13 mRNA expression in human articular chondrocytes and bovine chondrocytes
Jenniskens et al., Osteoarthritis Cartilage 2006 : TGFbeta2 and IGF1 had no effect on MMP activity