Gene interactions and pathways from curated databases and text-mining

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IGFBP1 — PRKAR1A

Text-mined interactions from Literome

Frost et al., Endocrinology 2000 : Conversely, a PKA inhibitor ( H-89 ) inhibited the ability of cAMP, but not IL-1beta to stimulate IGFBP-1 synthesis
Whitehouse et al., J Endocrinol 2002 : We have now investigated the responses to PKA activation and inhibition of PP1/2A and used PTP inhibitors to examine the relationship between the morphological changes and enhanced steroid production
Woo et al., Eur J Neurosci 2002 (Synaptic Transmission) : Our data show that genetic inhibition of PKA impairs L-LTP by reducing PKA mediated suppression of PP1/2A
Yeagley et al., Mol Endocrinol 2005 : PKA and Dex also synergistically induced a minimal 3 x glucocorticoid response element promoter, but inhibited Dex induction of the mouse mammary tumor virus and IGF binding protein 1 promoters, even though PKA alone did not regulate these promoters
Suwanichkul et al., J Biol Chem 1993 (Carcinoma, Hepatocellular...) : In addition, cotransfection of the catalytic subunit of cAMP dependent protein kinase A (PKA) with the native 1205-bp IGFBP-1 promoter construct stimulated IGFBP-1 promoter activity 3.9-fold, but the TAGCA mutation decreased by 73 % the ability of PKA to stimulate IGFBP-1 promoter activity above control levels