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IL12A — TGFB1
Text-mined interactions from Literome
Wilkinson et al., Scand J Immunol 2000
(Carcinoma...) :
A regulatory
role for
interleukin (IL)-12 in production of
transforming growth factor (TGF)-beta1 has been suggested, however, remains controversial ... In this study, we analyzed the
effect of
IL-12 on
TGF-beta1 expression in the human lines, K562 and A549, and in primary human monocytes and macrophages
Tada et al., Eur J Immunol 2001
:
Interestingly,
TGF-beta1 enhanced
IL-12 p40 production of anti-CD40/IFN-gamma stimulated LC, despite its down-regulatory effect on CD40 expression
Dey et al., Scand J Immunol 2007
(Leishmaniasis, Visceral) :
These chemokines induced the known pro-inflammatory cytokine
interleukin (IL)-12 secretion and
inhibited the secretion of anti-inflammatory cytokines IL-10 and
transforming growth factor-beta in infected macrophages
Zhao et al., J Huazhong Univ Sci Technolog Med Sci 2007
:
Effect of
TGF-beta1 on the expression of
IL-12 , IL-15, IL-18, IL-4 and IL-10 in heart transplantation rejection in rats
Zhang et al., Clin Neurol Neurosurg 2010
(Autoimmune Diseases...) :
IFNbeta inhibited IL-1beta, IL-23 and
transforming growth factor ( TGF ) -beta ( which induce Th17 cell differentiation ), and
induced IL-27,
IL-12p35 and IL-10 ( which suppress it ) in dendritic cells (DCs) and B-cells
Ye et al., J Leukoc Biol 1995
:
Furthermore, both
transforming growth factor-beta and genistein, a tyrosine kinase inhibitor, could
suppress IL-2 and
IL-12 signaling but CsA was generally inactive
Fulton et al., J Infect Dis 1998
:
Regulation of
interleukin (IL)-12 production by coexpression of tumor necrosis factor (TNF)-alpha, IL-10, and
transforming growth factor ( TGF ) -beta in human monocytes infected with Mycobacterium tuberculosis H37Ra was analyzed
Yasuda et al., J Clin Invest 1998
(Diabetes Mellitus, Type 1) :
Reverse transcription-PCR analysis revealed that local production of
IL-12p40 led to the decrease of interferon-gamma and the augmentation of
transforming growth factor-beta at the graft site