Gene interactions and pathways from curated databases and text-mining

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IL12RB1 — IL15

Text-mined interactions from Literome

Musikacharoen et al., Blood 2005 : Promoter analyses in a mouse macrophage cell line, RAW264.7, revealed that the 2508-bp region upstream of the transcriptional start site is sufficient for the full transcriptional activation of the IL12RB1 gene by IFN-gamma or IL-15 ... Consistently, IL-15 , as a histone deacetylase inhibitor, synergistically enhanced IL12RB1 gene expression and promoter activation by IFN-gamma through increased protein binding to ETS/PU.1 and IRE/ISRE sites
Wu et al., Eur J Immunol 1997 : Among 16 cytokines tested, IL-2, IL-7 and IL-15 markedly induced IL-12Rbeta1 expression and IL-12 binding on resting PBMC, whereas IL-1alpha and tumor necrosis factor-alpha had a minimal enhancing effect