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IL17A — TLR2

Text-mined interactions from Literome

Kim et al., Immunol Lett 2007 (Arthritis, Rheumatoid...) : TLR stimulation of RA-FLS also induced the production of IL-1beta and TNF-alpha to a lesser extent ; however, it had no effect on IL-17 production
van Beelen et al., Immunity 2007 (Bacterial Infections...) : MDP enhanced obligate bacterial Toll-like receptor ( TLR ) agonist induction of IL-23 and IL-1, which promoted IL-17 expression in T cells
Lee et al., J Rheumatol 2009 (Arthritis, Experimental) : Interleukin 17 (IL-17) increases the expression of Toll-like receptor-2 , 4, and 9 by increasing IL-1beta and IL-6 production in autoimmune arthritis ... To examine the effect of interleukin 17 (IL-17) on the expression of Toll-like receptor (TLR)-2 , 4, and 9 in collagen induced arthritis ( CIA ) in mice ... In CIA synoviocytes, IL-17 increased the expression of TLR-2 , 4, and 9, and this effect was significantly alleviated by neutralizing antibodies to IL-17, IL-1beta, and IL-6 ... IL-17 aggravates joint inflammation and destruction, and increases the synovial expression of TLR-2 , 4, and 9 by increasing IL-1beta and IL-6 ... These results imply that the IL-17 induced increase in expression of TLR-2 , 4, and 9, and IL-1beta and IL-6 production are involved in the IL-17 induced aggravation of arthritis
Cho et al., J Clin Invest 2010 (Staphylococcal Skin Infections) : Furthermore, IL-17 induction required IL-1, TLR2 , and IL-23 and was critical for host defense, since IL-17R-deficient mice had a phenotype similar to that of gammadelta T cell-deficient mice ... Furthermore, IL-17 induction required IL-1, TLR2 , and IL-23 and was critical for host defense, since IL-17R-deficient mice had a phenotype similar to that of gammadelta T cell-deficient mice
Ather et al., J Immunol 2011 (Disease Models, Animal...) : CD4 ( + ) T cells polyclonally stimulated in the presence of conditioned media from SAA exposed DCs produced IL-17 , and the capacity of polyclonally stimulated splenocytes to secrete IL-17 is dependent upon IL-1, TLR2 , and the NLRP3 inflammasome
Kwok et al., Arthritis Res Ther 2012 (Sjogren's Syndrome) : TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren 's syndrome ... The stimulation of TLR2, TLR4 and TLR6 additively induced the production of IL-17 and IL-23 from the PBMCs of pSS patients especially in the presence of TLR2 stimulation ... Our data demonstrate that TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in pSS
Nishimori et al., Infect Immun 2012 (Colitis...) : T cells incubated with supernatants from bone marrow derived dendritic cells ( BMDCs ) treated with curli fibrils released IL-17A in a TLR2 dependent manner in vitro
van den Brand et al., Ann Rheum Dis 2013 (Arthritis, Experimental) : Systemically, TLR4 in both BM-derived and resident cells contributed to IL-17 production by splenic T-cells, whereas in the DLNs of arthritic joints this was not the case
Rizzo et al., Int Immunopharmacol 2013 : Pre-treatment with the anti-TLR2/4 antibody abolished the inhibitory effects of L. plantarum on IL-17 and IL-23 production following S. pyogenes infection, indicating that L. plantarum downregulates TLR2/4 dependent IL-17 and IL-23 production