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ECM1 — IL1B
Text-mined interactions from Literome
Roman et al., Immunology 1999
:
In this study, we explored the intracellular mechanisms responsible for
ECM induction of
IL-1beta using human promonocytic U937 cells transfected with the full-length human IL-1beta gene promoter connected to a reporter gene ... These studies suggest that the signalling pathways which mediate
ECM induction of
IL-1beta expression in human monocytic cells converge at the level of PKC activation
Sassy-Prigent et al., Diabetes 2000
(Body Weight...) :
Glomerular
interleukin-1beta mRNA synthesis was also enhanced as early as day 1 and could be
involved in the increase in
ECM and adhesion molecule gene expressions
Murakami et al., Int Immunol 2001
:
In terms of ECM expression, adenosine and the adenosine receptor agonists, 2-CADO and CPA, enhanced constitutive and
IL-1beta induced expression of hyaluronate synthase mRNA, but not the mRNA levels of other
ECM , such as collagen type I, III and fibronectin
Yamaguchi et al., Arch Oral Biol 2005
(Anoxia) :
These findings suggest that hypoxia and
IL-1beta may
contribute to the degradation or remodelling of the
extracellular matrix ( ECM ) of the disc and may have a role in the pathogenesis of TMJ disorders
Wang et al., Life Sci 2007
:
In conclusion, emodin suppresses
IL-1beta induced MC proliferation and
ECM production in vitro