Gene interactions and pathways from curated databases and text-mining

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ECM1 — IL1B

Text-mined interactions from Literome

Roman et al., Immunology 1999 : In this study, we explored the intracellular mechanisms responsible for ECM induction of IL-1beta using human promonocytic U937 cells transfected with the full-length human IL-1beta gene promoter connected to a reporter gene ... These studies suggest that the signalling pathways which mediate ECM induction of IL-1beta expression in human monocytic cells converge at the level of PKC activation
Sassy-Prigent et al., Diabetes 2000 (Body Weight...) : Glomerular interleukin-1beta mRNA synthesis was also enhanced as early as day 1 and could be involved in the increase in ECM and adhesion molecule gene expressions
Murakami et al., Int Immunol 2001 : In terms of ECM expression, adenosine and the adenosine receptor agonists, 2-CADO and CPA, enhanced constitutive and IL-1beta induced expression of hyaluronate synthase mRNA, but not the mRNA levels of other ECM , such as collagen type I, III and fibronectin
Yamaguchi et al., Arch Oral Biol 2005 (Anoxia) : These findings suggest that hypoxia and IL-1beta may contribute to the degradation or remodelling of the extracellular matrix ( ECM ) of the disc and may have a role in the pathogenesis of TMJ disorders
Wang et al., Life Sci 2007 : In conclusion, emodin suppresses IL-1beta induced MC proliferation and ECM production in vitro